ADVIA Centaur® 에 대한 현장 안전성 서한

Field Safety Notice

2014-04-25

2014-05-16

Siemens healthcare diagnostics has shown that fluorescein-containing samples can show interference with advia centaur® systems tsh3 ultra, vitamin d and advia centaur brahms procalcitonin essay. research has shown that patients undergoing angiography with fluorescein can retain a small amount of fluorescein in the body from 48 to 72 hours after the procedure. in patients with renal insufficiency, retention may be significantly longer. samples containing fluorescein may give false-lower values ​​when tested with the advia _ centaur tsh3 ultra essay. on interference with florescein, the tsh3 ultra values ​​obtained may be less than 0.01 miu / l. these falsely reduced values ​​are important for monitoring patients with thyroid cancer because the physician can conclude that adequate suppression of tsh has been achieved. samples should be taken again after eliminating fluorescein to obtain tsh3 ultra results without interference. samples containing fluorescein may give false-lower values ​​when tested with the advia centaur brahms procalcitonin essay. for florescein interference, the values ​​obtained for procalcitonin may be less than <0.02 ng / ml. samples should be taken again after eliminating fluorescein in order to obtain safe results for procalcitonin without interference. samples containing fluorescein may give false elevations when tested with the advia centaur vitamin d essay. with florescein interference, the values ​​obtained for vitamin d may be > 150 ng / ml (> 375 nmol / l). samples should be taken again after eliminating fluorescein in order to obtain safe results for vitamin d without interference. the instructions for use for the advia centaur systems tsh3 ultra, vitamin d and advia centaur brahms procalcitonin tests will be supplemented to include a sentence concerning potential fluorescein interference.